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Bioinformatics Knowledge Database 國網中心生物知識庫與生物計算服務系統: 期刊導讀

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小鼠胚胎轉錄體整合性分析
監控全域的基因表現提供了一個觀看基因與調控訊息如何協同工作,引導胚胎發育的機會,現今發育生物學以及畸形學領域,面臨了一個需要自動存取基因表現特徵參考資料庫的需求,能夠測試胚胎轉錄體的遺傳與環境調控。
Posted by TerryYeh on Tuesday, July 31 @ 15:39:54 CST (1539 reads)
小鼠胚胎轉錄體整合性分析



排列排比的多序列排比法
動機:多序列排比是生物資訊領域中的基礎工作,目前的工具通常都是由合併次級排比(subalignment)作為排比的初始,之後便是重複拆解及合併次級排比來潤飾這個排比,即可以得到一個改進過的最終排比結果。
Posted by TerryYeh on Tuesday, July 31 @ 13:51:50 CST (1547 reads)
排列排比的多序列排比法



蛋白質體資料交換與儲存:通用標準與公開儲存的需求
經由全世界各實驗室產生的蛋白質體資料一直增加,導致了在資料儲存與取得上有了重大的問題。
Posted by TerryYeh on Thursday, July 26 @ 10:34:08 CST (1468 reads)
蛋白質體資料交換與儲存:通用標準與公開儲存的需求



序列相似性與功能相似性間的定量評估
背景:於基因體註解時,進行新蛋白質的註解,往往都採比較序列相似性的方法做未分析的第一步,然而序列的比較可能會導致功能指派錯誤的產生,因此,進行系統性的大規模以序列為基礎的功能指派分析是很重要的。
Posted by TerryYeh on Monday, July 23 @ 16:36:04 CST (1528 reads)
序列相似性與功能相似性間的定量評估



自動取出多序列排比的信賴區域
  背景:利用基因體註解轉換至另一個基因體,採用高品質的多序列排比是具決定性的,多序列排比方法為了要達成增加測試組的平均正確性,往往會忽略掉序多單一排比的正確性。
Posted by TerryYeh on Wednesday, July 18 @ 15:42:24 CST (1248 reads)
自動取出多序列排比的信賴區域



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