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科學家找到老鼠的耳聾基因
Posted on Tuesday, February 14 @ 10:08:47 CST by ming

科學家已找出造成老鼠耳聾的基因,有助於了解人類耳聾的成因及治療方法。

據美國之音報導,美國華盛頓大學研究人員將老鼠進行基因工程改造,使之生下來就缺乏FGF20基因,並觀察其表現,發現這些老鼠聽不到聲音,但是其他功能未受影響,壽命也正常。

研究人員發現老鼠的內耳有不同程度的變化;外毛細胞對聽力很重要,通常聽力正常的老鼠外毛細胞(outer hair cell)長得很茂密,但是這些除去FGF20基因老鼠的外毛細胞比一般老鼠少很多,也長得稀稀疏疏,不過內毛細胞(inner hair cell)未受影響,因此發現FGF20基因造成外毛細胞發育不全,進一步影響老鼠的聽力。...(詳全文)



轉載自 國科會簡訊網

 
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