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減緩乳癌擴散的新標靶
Posted on Monday, January 09 @ 09:27:25 CST by ming

加拿大麥吉爾大學健康研究中心 (Research Institute of the McGill University Health Centre, RI-MUHC) 的 Richard Kremer 博士領導的研究團隊已經發現一個新的可能標靶,能減緩乳癌腫瘤的擴展和轉移(metastasis)。乳癌透過轉移擴散到身體的其他部位(最常擴散到骨骼和肺)會引起患者的併發症。這項研究成果發表於近期的《臨床研究期刊(Journal of Clinical Investigation, JCI)》,研究指出有一種特定的蛋白質會影響疾病在原腫瘤區以外的進展。"

研究人員發現這種稱為副甲狀腺賀爾蒙相關蛋白(parathyroid hormone-related protein, PTHrP)特定標靶出現在高階癌症,其參與了乳癌的開始、進展和轉移擴散的關鍵階段。麥吉爾大學醫學系教授、RI-MUHC肌肉骨骼研究所(Musculoskeletal Axis)聯合主任Richard Kremer博士表示,「我們希望透過減少此類特定蛋白質產生的策略,能在預防乳癌復發、增長及發展上有重大的效果。」...(詳全文)



轉載自 國科會簡訊網

 
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