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Posted on Wednesday, August 22 @ 10:42:18 CST by xeme

美國賓州大學醫學院的研究者,最近發現了Bcl-3 蛋白如何藉由干擾泛蛋白化( ubiquitination)的過程來調控外物侵襲時的發炎反應。這項首次發現 Bcl-3蛋白與泛蛋白化之間相關性的研究發表於 Science期刊中,為免疫領域的研究帶 來新的觀點,對免疫疾病的治療法帶來新希望。泛蛋白化(ubiquitination )是細胞內清除無用或錯誤蛋白質的代謝過程;當細胞製造出有問題的蛋白,或是暫時 不需要某些功能的蛋白時,泛蛋白(ubiquitin )會結合到要分解的蛋白上標定,讓細胞進一步進行分解反應。.....(詳全文 )




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